Characterization of Multi Heavy Metal Tolerant Bacterial Isolate from Middle Gangetic Plains, India.

Authors

  • Sunita Singh School of Biotechnology and Bioinformatics, D Y Patil Deemed to be University, Navi Mumbai, India https://orcid.org/0000-0001-8163-6972
  • Ruchi Dube School of Biotechnology and Bioinformatics, D. Y. Patil Deemed to be University, Navi Mumbai, India
  • Arpita Gupte School of Biotechnology and Bioinformatics, D. Y. Patil Deemed to be University, Navi Mumbai, India https://orcid.org/0000-0003-4520-5782

DOI:

https://doi.org/10.55863/ijees.2024.0009

Keywords:

Heavy metal tolerant bacteria, Biocompatibility, Antibiotic resistance

Abstract

The research focuses on antibiotic resistance profiles and bacterial compatibility in multi-heavy metal-tolerant bacterial strains. It reveals significant concerns about antibiotic resistance in these bacteria, including resistance to penicillin, streptomycin, tetracycline, ampicillin, and vancomycin. Notably, 96% of the isolates exhibited resistance to vancomycin. The study emphasizes the need for prudent antibiotic use to combat its resistance. Conversely, tetracycline and penicillin showed lower resistance levels at 85 and 77%, respectively, in line with previous research showing diverse resistance patterns among antibiotics and bacterial strains. This highlights the complexity of antibiotic resistance mechanisms, requiring a comprehensive approach. The research also explores bacterial compatibility, revealing that 23 out of 46 bacterial isolates exhibited complete compatibility, suggesting cooperative interactions. Some specific isolates displayed compatibility at 96%, while few had lower compatibility at 75%, indicating the potential for antagonistic interactions. In summary, this study underscores the complex dynamics of antibiotic resistance and compatibility in multi-heavy metal-tolerant bacteria, with implications for clinical antibiotic use and microbial interactions in natural environments. With advancement in microbial ecosystems research, it is essential to unravel these mechanisms and deliberate strategies for addressing antibiotic resistance as a sustainable approach.

 Keywords: Heavy metal tolerant bacteria, Biocompatibility, Antibiotic Resistance

Author Biographies

Sunita Singh, School of Biotechnology and Bioinformatics, D Y Patil Deemed to be University, Navi Mumbai, India

Dr. Sunita Singh was an ex-DAE Fellow and completed her Ph. D from B. A. R. C, Mumbai. Currently she is serving, School of Biotechnology and Bioinformatics, D.Y. Patil Deemed to be University as Associate Professor and Section Head- Biotechnology. Her area of research has been Molecular Barcoding, Plant Physiology and Stress biology, Environmental Microbiology

Ruchi Dube, School of Biotechnology and Bioinformatics, D. Y. Patil Deemed to be University, Navi Mumbai, India

Ms. Ruchi Dube is a Ph.D. Student pursuing her Ph.D. at the D.Y. Patil Deemed to be University, School of Biotechnology and Bioinformatics. She has completed her MSc from the same University.

Arpita Gupte, School of Biotechnology and Bioinformatics, D. Y. Patil Deemed to be University, Navi Mumbai, India

Dr. Arpita Gupte an Ex- DAE fellow is a Ph.D.in Biochemistry (B.A.R. C). Currently she is serving as Section Head and Course Coordinator (Food Science and Technology) at School of Biotechnology and Bioinformatics, D. Y. Patil Deemed to be University, Navi Mumbai. Her area of research is new product development, environmental Biotechnology, Bioremediation.  

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Published

2024-01-02

How to Cite

Singh, S., Dube, R., & Gupte, A. (2024). Characterization of Multi Heavy Metal Tolerant Bacterial Isolate from Middle Gangetic Plains, India. International Journal of Ecology and Environmental Sciences, 50(3), 349–353. https://doi.org/10.55863/ijees.2024.0009