Pesticide Induced Oxidative Stress on Non-Target Organism Labeo rohita


  • Ravi Sekhar Pesala Government College for Men (Autonomous) Kadapa
  • Savithri Yerragudi



Cypermethrin, Chlorphyrifos, Labeo rohita, XOD, SOD, CAT, Liver tissue, Gill tissue


The application of pesticides in agricultural activities can result in their runoff into water bodies, causing water contamination. This contamination poses a threat to water quality, rendering it harmful to aquatic organisms. This study investigated the acute toxic effects of the synthetic pyrethroid pesticide cypermethrin and the organophosphate pesticide chlorpyrifos, both individually and in combination, on the antioxidant enzyme activities viz., Xanthine oxidase (XOD), Superoxide dismutase (SOD) and Catalase (CAT) in the liver and gill tissues of the fish, Labeo rohitaL. rohita were exposed to sub-lethal concentrations of cypermethrin and chlorpyrifos individually and in combination for 7 days. The concentrations used were 1/10th of the LC50 dosage for individual treatments (0.308 µg/L for cypermethrin and 44.28 µg/L for chlorpyrifos) and 1/20th of the LC50 for the combined treatment (0.154µg/L for cypermethrin + 22.14µg/L for chlorpyrifos). The findings of this study revealed a significant (P<0.05) increase in the activities of Xanthine oxidase (XOD), Superoxide dismutase (SOD) and Catalase (CAT) in both liver and gill tissues compared to the control group. The observed alterations were more pronounced in the combined treatment as compared to individual exposures, suggesting a potential synergistic effect of cypermethrin and chlorpyrifos.


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How to Cite

Pesala, R. S., & Yerragudi, S. (2024). Pesticide Induced Oxidative Stress on Non-Target Organism Labeo rohita. International Journal of Ecology and Environmental Sciences, 50(4), 585–590.